After starting 2006 with special appearances in three films, Chopra starred in Rakesh Roshan's superhero film Krrish (a sequel to the 2003 science-fiction film Koi... Mil Gaya). Co-starring with Hrithik Roshan, Rekha andNaseeruddin Shah, Chopra played a young television journalist who schemes to take advantage of an innocent young man with remarkable physical abilities, but eventually falls in love with him. The film was the second-highest-grossing film of the year in India and grossed over ₹1.17 billion(US$18 million) worldwide attaining ablockbuster status.[64] Her next film wasDharmesh Darshan's romantic comedy Aap Ki Khatir, co-starring Akshaye Khanna, Ameesha Patel and Dino Morea. Neither the film nor Chopra's performance were well received.[65]Sukanya Verma of Rediff.com stated that Chopra's portrayal of Anu was "erratically sketched" and that her character was never consistent: "first flaky, then cool, and later, sensitive".[66]
Chopra's final release of 2006 was Farhan Akhtar's action-thriller Don (a remake of the1978 film of the same name), with Shah Rukh Khan. Chopra portrayed Roma (played byZeenat Aman in the original film), who joins the underworld to avenge Don for killing her brother. Chopra received martial-arts training for her role in the movie, and performed her own stunts.[67] The film was declared a box-office success in India and overseas, with revenues of ₹1.05 billion (US$16 million).[50]Raja Sen of Rediff.com found Chopra to be film's "big surprise"; he believed that Chopra convincingly portrayed Roma, "looking every bit the competent woman of action" and wrote "This is an actress willing to push herself, and has definite potential for screen magic. Not to mention a great smile.